Zhanghua Chen, PhD
Assistant Professor of Population and Public Health Sciences
Dr. Zhanghua Chen is an environmental epidemiologist and biostatistician with multidisciplinary expertise in environmental health, biostatistics, epidemiology, clinical medicine, obesity and diabetes pathophysiology, genomics, metabolomics, and data science. She has a strong track record in environmental health research with particular interests in the health effects of early-life environmental exposures in children and adults, the epidemiology of diabetes and obesity, and methods of multi-omics studies.
Dr. Chen aims to contribute her research to early prevention and treatment of complex diseases. She is creative, collaborative and highly productive. She is establishing a novel research area in environmental epidemiology by leveraging the advanced metabolomics and multi-omics approaches. Dr. Chen is the principal investigator on the NIEHS-supported K99/R00 Pathway to Independence Award: ?Metabolomic Signatures Linking Air Pollution, Obesity and Diabetes?. She has also published many papers in well-received medical journals such as Diabetes Care and American Journal of Respiratory and Critical Care Medicine. Her accomplishments in environmental health research have received wide media attention from national and international news agencies, e.g., Reuters and Xinhua News Agency.
Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults.
Environ Int. 2020 Dec;145:106091. doi: 10.1016/j.envint.2020.106091. Epub 2020 Sep 3. PubMed PMID: 32892005;
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.
Eur J Epidemiol. 2019 Mar;34(3):279-300. doi: 10.1007/s10654-019-00502-9. Epub 2019 Mar 18. PubMed PMID: 30887376; PubMed Central PMCID: PMC6447695.
Near-roadway air pollution exposure and altered fatty acid oxidation among adolescents and young adults - The interplay with obesity.
Environ Int. 2019 Sep;130:104935. doi: 10.1016/j.envint.2019.104935. Epub 2019 Jun 22. PubMed PMID: 31238265; PubMed Central PMCID: PMC6679991.
Perfluoroalkyl substances, metabolomic profiling, and alterations in glucose homeostasis among overweight and obese Hispanic children: A proof-of-concept analysis.
Environ Int. 2019 May;126:445-453. doi: 10.1016/j.envint.2019.02.047. Epub 2019 Mar 4. PubMed PMID: 30844580; PubMed Central PMCID: PMC6555482.
Does early onset asthma increase childhood obesity risk? A pooled analysis of 16 European cohorts.
Eur Respir J. 2018 Sep;52(3). doi: 10.1183/13993003.00504-2018. Epub 2018 Sep 27. PubMed PMID: 30209194; PubMed Central PMCID: PMC6443037.